Jane Dotson
Addyi (flibanserin) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in premenopausal women who have not had problems with low sexual desire in the past. It is not meant to be used to enhance sexual performance or to treat HSDD in men or children. Addyi is not covered by most Medicare and insurance plans, but there are ways to reduce the cost of a prescription.
| Characteristics | Values |
|---|---|
| What is Addyi (flibanserin) used for? | To treat hypoactive (low) sexual desire disorder (HSDD) in premenopausal women who have not had problems with low sexual desire in the past. |
| Is Addyi covered by medical insurance? | Addyi is not covered by most Medicare and insurance plans. |
| What are the side effects of Addyi? | Sleepiness, low blood pressure, fainting (loss of consciousness), and hypersensitivity reactions (including anaphylaxis, angioedema, pruritus, and urticaria). |
| What should you avoid when taking Addyi? | Grapefruit juice, alcohol, St. John's Wort, ginkgo, resveratrol, cimetidine, and certain prescription and over-the-counter medications. |
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What You'll Learn
Addyi is not covered by most insurance plans
Addyi (flibanserin) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in premenopausal women. It is not to be used for women who have gone through menopause, men, or children. It is also not to be used to enhance sexual performance.
Addyi is not covered by most insurance and Medicare plans. However, there are ways to reduce the cost of an Addyi prescription. GoodRx has partnered with InsideRx and Sprout Pharmaceuticals to reduce the price for this prescription. Check their website for savings tips for co-pay cards, assistance programs, and other ways to save money.
Additionally, a limited set of drugs administered in a doctor's office or hospital outpatient setting may be covered under Medical Insurance (Part B). It depends on which coverage stage you are in. In the Post-Deductible (or Initial Coverage) stage, you pay your copay and your plan covers the rest of the drug cost. In the Post-Donut Hole (or Catastrophic Coverage) stage, Medicare should cover most of the cost of your drug.
It is important to note that taking Addyi with certain other medications can increase the amount of Addyi in your blood, leading to clinically significant drug interactions. These interactions may cause severe low blood pressure, fainting (loss of consciousness), and sleepiness. Before you start taking Addyi, tell your doctor or pharmacist about all your medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
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Addyi is a prescription medicine for premenopausal women with HSDD
Addyi, also known as flibanserin, is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in premenopausal women. HSDD is characterised by low sexual desire that causes distress or interpersonal difficulty and is not due to a medical or mental health problem, relationship issues, or substance use. Addyi is specifically indicated for women who have not had problems with low sexual desire in the past but are now experiencing low sexual desire regardless of the type of sexual activity, the situation, or the sexual partner.
Addyi is not suitable for women who have gone through menopause, men, or children. It is also not intended to enhance sexual performance. As a prescription medication, Addyi is typically obtained through a doctor or pharmacist, who can provide guidance on its use and any potential side effects.
It is important to note that Addyi may interact with other medications, herbal supplements, or substances, leading to increased side effects. For example, taking Addyi with certain prescription medications, such as antibiotics or medicines for depression, may increase the amount of Addyi in the blood, resulting in severe low blood pressure, fainting, and sleepiness. Similarly, consuming alcohol within two hours of taking Addyi or during waking hours can increase the risk of these side effects. Therefore, patients taking Addyi should avoid activities requiring full alertness, such as driving or operating machinery, for at least six hours after each dose.
Additionally, Addyi should not be taken with certain herbal supplements, such as St. John's Wort, ginkgo, or resveratrol, or specific over-the-counter medications without consulting a doctor first. Patients should always inform their doctor or pharmacist about all the medications they are currently taking, including prescription drugs, vitamins, and herbal supplements, to ensure safe use.
In terms of cost, Addyi is not typically covered by most insurance plans or Medicare. However, there may be ways to reduce the cost, such as through co-pay cards, assistance programs, or partnerships with pharmaceutical companies to offer discounted prices.
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Addyi should not be taken with certain medicines or herbal supplements
Addyi (flibanserin) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women who have not gone through menopause and who have not had problems with low sexual desire in the past. It is not covered by most Medicare and insurance plans.
Some commonly prescribed medications that should be avoided while taking Addyi include antibiotics, nefazodone (a medicine used to treat depression), and certain medicines used to treat HIV-1 infection, fungal infections, hepatitis-C infections, high blood pressure, chest pain, or other heart problems. It is crucial to refer to the Addyi Medication Guide for a comprehensive list of medications to avoid.
Additionally, you should not take the herbal supplements St. John's Wort, ginkgo, or resveratrol, or certain over-the-counter medicines such as cimetidine, without consulting your doctor first. Taking Addyi with these herbal supplements and over-the-counter medicines may increase your risk of low blood pressure, fainting (loss of consciousness), and sleepiness.
Furthermore, alcohol consumption should be avoided while taking Addyi. Drinking alcohol with Addyi can cause dangerous or unwanted side effects, including severe low blood pressure and fainting (syncope). If you have consumed one or two standard alcoholic drinks, it is recommended to wait for at least two hours before taking Addyi at bedtime or skipping the dose altogether. If you have consumed three or more standard alcoholic drinks, it is advised to skip the Addyi dose for that day.
Lastly, grapefruit products, including grapefruit juice, should be avoided during Addyi treatment as they can lead to unwanted side effects.
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Addyi should not be taken with grapefruit juice
Addyi (flibanserin) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women who have not gone through menopause and who have low sexual desire no matter the type of sexual activity, the situation, or the sexual partner. It is not covered by most Medicare and insurance plans.
Grapefruit juice may affect people differently, even when they take the same drug. This is because the amount of the CYP3A4 enzyme in the intestine varies from person to person. Some people have a lot of this enzyme, while others have very little. So, grapefruit juice may impact the concentration of flibanserin in the blood, which can cause severe hypotension and syncope. In a study of 26 healthy female subjects, 240 mL of grapefruit juice increased flibanserin 100 mg single-dose exposure (AUC) by 1.4-fold and Cmax by 1.1-fold compared to flibanserin 100 mg alone.
The severity of the interaction can be different depending on the person, the drug, and the amount of grapefruit juice consumed. With most drugs affected by grapefruit juice, more of the drug enters the blood, and when there is too much drug in the blood, you may experience more side effects. For example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may remain in your body, increasing your risk for liver and muscle damage, which can lead to kidney failure.
Therefore, it is important to avoid grapefruit juice while taking Addyi to prevent any potential negative side effects.
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Addyi can cause sleepiness, low blood pressure, and fainting
Addyi (flibanserin) is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in premenopausal women who have not had problems with low sexual desire in the past. It is not to be used to enhance sexual performance or by women who have gone through menopause, men, or children. Addyi is not covered by most Medicare and insurance plans.
It is important to note that you should not take Addyi with certain medicines or herbal supplements as it can increase the amount of Addyi in your blood, leading to clinically significant drug interactions. These interactions may cause severe low blood pressure, fainting, and sleepiness. Before you start taking Addyi and throughout treatment, it is important to tell your doctor or pharmacist about all your medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Some commonly prescribed medications that you should avoid while taking Addyi include antibiotics, nefazodone (a medicine used to treat depression), and certain medicines used to treat HIV-1 infection, fungal infections, hepatitis-C infections, high blood pressure, chest pain, or other heart problems. You should also avoid taking the herbal supplements St. John's Wort, ginkgo, or resveratrol, or certain over-the-counter medicines such as cimetidine, until you have talked to your doctor.
If you take Addyi and feel lightheaded or dizzy, lie down right away. Get emergency medical help or ask someone to get emergency medical help for you if the symptoms do not go away or if you feel like you could faint. If you faint, tell your doctor as soon as you can.
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Frequently asked questions
Addyi is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in premenopausal women who have not had problems with low sexual desire in the past.
Addyi is not covered by most Medicare and insurance plans. However, it depends on which coverage stage you are in. In the Post-Donut Hole (or Catastrophic Coverage) stage, Medicare should cover most of the cost of your drug.
Take this medicine by mouth with water. Take it as directed on the prescription label. This medicine should only be taken at bedtime. Do not take this medicine with grapefruit juice or alcohol.
Sleepiness is a common side effect of Addyi. Taking Addyi can also increase your risk of low blood pressure and fainting (loss of consciousness).
Do not take Addyi with certain prescription medicines, over-the-counter medicines, or herbal supplements. Some common medications to avoid include antibiotics, medicines for fungal infections, and St. John's Wort. Always talk to your doctor before starting any new medication.
