Radioactive iodine therapy (RAI) is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. It is a type of nuclear medicine treatment that uses radioactive iodine (I-131) to target and destroy thyroid cells. This treatment is considered a form of radiation therapy, and as such, there are certain precautions that patients must take to protect those around them from radiation exposure. These precautions can include maintaining a distance of at least 3 feet from people and sleeping alone for a few days after the treatment.
Characteristics | Values |
---|---|
Used for | Treatment of hyperthyroidism and certain types of thyroid cancer |
Treatment type | Nuclear medicine treatment |
Effectiveness | High success rate |
Treatment procedure | Oral capsule or liquid dose, or IV injection |
Side effects | Neck tenderness and swelling, dry mouth, altered sense of taste, nausea, low sperm count, irregular periods, thyroid storm |
Precautions | Avoid close contact with others, especially pregnant women and children, for a few days after treatment; follow radiation safety instructions |
Duration | Brief procedure, but preparation and post-treatment precautions are time-intensive |
Isolation period | Typically 3-5 days, but can be up to 2 weeks depending on the case |
Hospitalization | May be required for a few days after treatment |
Insurance | Call insurance company to check if prior authorization is needed |
What You'll Learn
- Radioactive iodine therapy is used to treat hyperthyroidism and certain types of thyroid cancer
- It is a safe, effective, and well-established treatment
- Patients must follow a low-iodine diet for 1-2 weeks before treatment
- Radioactive iodine therapy is a systemic and targeted treatment
- Side effects may include dry mouth, altered sense of taste, and neck tenderness and swelling
Radioactive iodine therapy is used to treat hyperthyroidism and certain types of thyroid cancer
Radioactive iodine therapy is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. The thyroid gland is a butterfly-shaped gland located in the front of the neck. It produces hormones that help regulate metabolism.
The thyroid cell's job is to make hormones that govern various body processes, such as temperature regulation and metabolism. There are two types of thyroid cells: follicular and para-follicular. Follicular thyroid cells need iodine from food to function properly. Radioactive iodine therapy uses this mechanism to diagnose and treat thyroid disorders.
Radioactive iodine therapy is a radiopharmaceutical procedure that uses radioactive isotopes, specifically iodine-131 (I-131), to treat hyperthyroidism and certain types of thyroid cancer. It is a type of nuclear medicine treatment. The procedure itself is generally brief and simple, but there are several preparation steps and post-procedure precautions to take.
For hyperthyroidism treatment, a low dose of I-131 is given to destroy overactive thyroid tissue. This is used for conditions such as Graves' disease or toxic thyroid nodules. For thyroid cancer treatment, larger doses of I-131 are used to destroy remaining thyroid cancer cells after surgery. This treatment is effective for papillary and follicular thyroid cancer that has spread to the neck or other body parts.
Radioactive iodine therapy is generally safe, but there are some side effects and risks. One common side effect is mild pain in the neck, which can be treated with over-the-counter medications. Other possible side effects include neck tenderness and swelling, salivary gland swelling, and inflammation of the stomach lining. Long-term side effects may include low or absent thyroid hormone levels, requiring lifelong hormone replacement medication.
There are also risks associated with radioactive iodine therapy. It may cause temporary infertility in men and irregular periods in women for up to a year after treatment. There is also a slightly increased risk of developing salivary gland cancer, thyroid cancer (if treated for hyperthyroidism), and other secondary cancers. It is important to follow the precautions provided by the healthcare team to minimize radiation exposure to others, especially pregnant women and children.
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It is a safe, effective, and well-established treatment
Radioactive iodine therapy is a safe, effective, and well-established treatment for hyperthyroidism and certain types of thyroid cancer. It has been used to treat thyroid cancer since the early 1940s and is considered the first true targeted therapy. The procedure is generally brief and simple, but there are several preparation steps and precautions to be aware of.
Radioactive iodine therapy specifically targets thyroid cells, destroying them with radiation while leaving the rest of the body largely unaffected. This treatment is made possible by the fact that the thyroid gland needs iodine to produce thyroid hormones, which regulate body processes such as temperature and metabolism. Typically, iodine is obtained through diet, but in radioactive iodine therapy, the thyroid absorbs radioactive iodine, which kills the thyroid cells.
The treatment is usually administered orally in the form of a pill or liquid, but it can also be delivered through an IV injection. The procedure is generally well-tolerated, and side effects are often temporary. Short-term side effects may include neck tenderness and swelling, salivary gland swelling, and inflammation of the stomach lining. One long-term side effect is very low or absent thyroid hormone levels, requiring lifelong hormone replacement medication.
Radioactive iodine therapy is considered safe for the patient, but precautions must be taken to protect others from radiation exposure in the days following the procedure. Patients will be advised to maintain a distance of at least 3 feet from others and 6 feet from pregnant people and children for a certain period. They may also be instructed to drink plenty of fluids to "flush out" the radiation and follow hygiene practices to reduce the risk of exposure to others.
The success rate of radioactive iodine therapy is high, with one study showing an 87.7% cure rate for hyperthyroidism with a single dose of radioactive iodine. It is an effective and reliable treatment option for certain thyroid conditions.
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Patients must follow a low-iodine diet for 1-2 weeks before treatment
Patients must follow a low-iodine diet for 1-2 weeks before radioactive iodine therapy as it helps the treatment work more effectively. This is because the thyroid gland absorbs and stores most of the iodine in the body. A low-iodine diet will help the thyroid cells absorb the radioactive iodine, which is the main component of the treatment.
A low-iodine diet involves restricting food that is high in iodine, as well as food that affects iodine absorption. This includes:
- Dairy products (milk, cheese, cream, yoghurt, butter, and ice cream)
- Whole eggs, egg yolks, and foods containing whole eggs
- Seafood (all fish and shellfish)
- Bread products made with dough conditioners like sodium iodate
- Soy products (soy sauce, soy milk, and tofu)
- Blackstrap (sulfured) molasses
- Cured meats or fish (ham, bacon, lox, and corned beef)
- Red-coloured food made with FD&C red dye #3
- Foods containing additives like carrageenan, agar-agar, alginates, or nori
It is also important to check medications and supplements for iodine-containing substances. Some medications and supplements contain the iodine-containing colourant FD&C red dye #3, also known as erythrosine. Herbal supplements are also a common source of iodine, and their labels may not always disclose this.
A low-iodine diet is not recommended on an ongoing basis as it deprives the body of an essential mineral. However, it is a crucial step in preparing for radioactive iodine therapy and can increase the odds of an optimal response to the treatment.
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Radioactive iodine therapy is a systemic and targeted treatment
Radioactive iodine therapy involves the use of radioactive isotopes, specifically iodine-131 (I-131), to diagnose or treat disease. The iodine molecules emit radiation, which destroys the malfunctioning thyroid cells. The thyroid cells absorb the radioactive iodine, which kills them using radiation. This treatment is considered safe and well-tolerated, with little exposure to the rest of the body's cells.
Before administering radioactive iodine therapy, patients may be advised to follow a low-iodine diet for a few days. This deprives the thyroid of iodine and makes it more receptive to the treatment. During the treatment, patients are given radioactive iodine molecules in the form of a pill. Since thyroid cells cannot distinguish between radioactive and non-radioactive iodine, they absorb it quickly.
Radioactive iodine therapy is a systemic treatment because it targets the thyroid specifically, and it is a targeted treatment because it can be used to find and destroy cancerous cells, even if they have spread to other parts of the body.
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Side effects may include dry mouth, altered sense of taste, and neck tenderness and swelling
Radioactive iodine therapy is a generally safe and effective treatment for hyperthyroidism and certain thyroid cancers. It is a brief and simple procedure, but it requires careful preparation and post-therapy precautions.
Radioactive iodine therapy (RAI) involves the patient taking in radioactive iodine, which kills thyroid cells using radiation. This is usually administered orally, but it can also be injected intravenously. The treatment is targeted at thyroid cells, with little exposure to the rest of the body's cells. However, patients can emit small amounts of radiation that could affect others, so precautions must be taken.
One of the short-term side effects of RAI therapy is neck tenderness and swelling. This is accompanied by swelling of the salivary (spit) glands, which may manifest as cheek swelling. To alleviate this, patients are advised to chew gum or suck on hard candy after the procedure. RAI therapy can also cause inflammation of the stomach lining (gastritis) and dry mouth.
In addition, RAI therapy can lead to a reduction in tear formation, resulting in dry eyes. Patients who wear contact lenses should consult their doctor about how long to refrain from using them.
The long-term side effects of RAI therapy include very low or absent thyroid hormone levels, requiring lifelong hormone replacement medication. This is a common and expected outcome of the treatment.
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Frequently asked questions
Radioactive Iodine Therapy (RAI) is a treatment for hyperthyroidism and certain types of thyroid cancer. It uses radioactive iodine, typically Iodine-131 (I-131), which is absorbed by the thyroid gland and destroys its cells.
The thyroid requires iodine to function, which it usually gets from food. In RAI therapy, the thyroid absorbs radioactive iodine, which kills thyroid cells using radiation.
Short-term side effects may include neck tenderness and swelling, salivary gland swelling, and inflammation of the stomach lining. Long-term effects can include very low or absent thyroid hormone levels, requiring lifelong hormone replacement medication.
You will need to follow a low-iodine diet for at least a week before treatment. You may also need to stop taking certain medications, and your doctor will advise you on any other necessary preparations.